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بروفين يعمل مباشرة على مصدر الألم5,8,14,15

بروفين ينتمي إلى العقاقير الغير استيرويدية المضادة للإلتهابات (المسكنات) ليست مشتقة من الكورتيزون وكذلك مضادات الفلوجيستيكش (مضادات الالتهابات) التي تعالج أعراض الالتهابات، مثل الألم والتورم.

يثبط بروفين البروستاجل اندين16,17. التى تسبب الألم والحمى والالتهاب فيختفي بذلك الألم والحمى والالتهاب. في حين أن الأدوية مثل الباراسيتامول تقلل من إنتقال إشارات الألم إلى المخ أما مضادات الالتهاب غير الستيرويدية مثل ايبوبروفين تعمل مباشرة على سبب الألم وتستهدف الأنسجة المتضررة16,17. لتكافح الأسباب الفعلية للألم مثل الإلتهابات على الفور18.

أو بعبارة أخرى: يؤثر بروفين على مصدر الألم بإحتواءه على المادة الفعالة ايبوبروفين وكذلك يحارب التهابات الأنسجة. إيبوبروفين هو مسكن "حمضي" (ذلك بسبب درجة حموضته العالية)، ولذلك فإنه يخترق الأنسجة الملتهبة بطريقة فعالة12.

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